Author information
- 1. International Center for Cosmetic Medicine, Sydney, NSW, Australia. fbaez@optusnet.com.au
Abstract
BACKGROUND:
Light-emitting diode (LED) therapy is an increasingly popular methodology for the treatment of sun damage. Combination use of light wavelengths reported to stimulate collagen synthesis and accelerate fibroblast-myofibroblast transformation may display a composite rejuvenative effect.
OBJECTIVE:
To clinically assess reduction in sun damage signs following a 5-week course of LED therapy and to assess subject's perception of the treatment.
METHODS:
Thirteen subjects with wrinkles or fine lines in the periorbital and nasolabial region and those presenting Glogau scale photodamage grade II-III received nine 20-min duration light treatments using the Omnilux LED system. The treatments combined wavelengths of 633 and 830 nm at fluences of 126 and 66 J/cm(2), respectively. Sun-damage reduction was assessed at 6, 9, and 12 weeks by clinical photography and patient satisfaction scores.
RESULTS:
The majority of subjects displayed "moderate" (50%) or "slight" (25%) response to treatment at investigator assessment. Treatment of the periorbital region was reported more effective than the nasolabial region. At 12-week follow-up, 91% of subjects reported improved skin tone, and 82% reported enhanced smoothness of skin in the treatment area.
CONCLUSION:
Good response to LED therapy has been shown in this modest sample. Larger trials are needed to assess optimum frequency of light treatments and overall treatment time.
Original Source:
https://www.ncbi.nlm.nih.gov/pubmed/17760698
